Established in 1974, Galeria Luisa Strina helped to promote the careers of a whole generation of new conceptual artists from Brazil, including Antonio Dias, Cildo Meireles, Tunga and Waltercio Caldas. In 1992, the gallery was the first in Latin America to take part in the Art Basel fair.

Luisa Strina began working with emerging Brazilian artists such as Alexandre da Cunha, Fernanda Gomes and Marepe. Throughout the 2000s, the group was expanded to include Latin American names - Carlos Garaicoa, Jorge Macchi, Juan Araujo and Pedro Reyes - and well established women artists such as Laura Lima, Leonor Antunes and Renata Lucas.

In the last decade, the gallery has consolidated its trajectory with the representation of prestigious names in both modern and contemporary art scene such as Alfredo Jaar and Anna Maria Maiolino, as well as younger artists such as Bruno Baptistelli and Panmela Castro.